SCHEMBL11276299

SCHEMBL11276299

COP(=S)(OC)Oc1nc(C)n(-c2ncc(Br)cn2)n1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11253529 0.86 KDM4E (0.37) KDM4E
SCHEMBL11253521 0.77 KDM4E (0.34) KDM4E
SCHEMBL10383051 0.73 KIT (0.36) KDM4ETDP1
SCHEMBL11388310 0.69 MAPT (0.45) KDM4EMEN1KMT2A
SCHEMBL11083173 0.67 KDM4E (0.44) KDM4E
SCHEMBL11395420 0.67 PHGDH (0.34)
SCHEMBL31648661 0.62 KDM4E (0.33) KDM4E
SCHEMBL24971612 0.60 KDM4E (0.47) KDM4E
SCHEMBL11256442 0.59 KDM4E (0.32) KDM4E
SCHEMBL2899562 0.59 KDM4E (0.50) KDM4EKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4357328-A Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides THE DOW CHEMICAL CO. (US) 1982-11-02 US claimed