SCHEMBL11083173

SCHEMBL11083173

Cc1nc(O)nn1-c1ncc(Br)cn1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
TIPARP Q7Z3E1 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11253529 0.73 KDM4E (0.37) KDM4E
SCHEMBL24971612 0.69 KDM4E (0.47) KDM4EALDH1A1
SCHEMBL2899562 0.68 KDM4E (0.50) KDM4EALDH1A1
SCHEMBL11276299 0.67 KDM4E (0.35) KDM4E
SCHEMBL11088112 0.65 KDM4E (0.38) KDM4EALDH1A1
SCHEMBL146602 0.65
SCHEMBL1403777 0.64 KDM4E (0.46) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL31648918 0.64 KDM4E (0.38) KDM4E
SCHEMBL20696081 0.62
SCHEMBL27849631 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4433148-A CHEMICAL INTERMEDIATES FOR TRIAZOLYL PHOSPHORUS INSECTICIDWS THE DOW CHEMICAL CO. (US) 1984-02-21 US claimed