SCHEMBL2899562

SCHEMBL2899562

Cc1cc(C)n(-c2ncc(Br)cn2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HTT P42858 2/20 0.47
ALOX15 P16050 5/20 0.45
BCL6 P41182 1/20 0.44
GAA P10253 2/20 0.44
NPC1 O15118 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
CYP1A2 P05177 2/20 0.44
RAB9A P51151 2/20 0.44
CYP2C9 P11712 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22560253 0.84 MAPT (0.53) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL19105558 0.78 LMNA (0.50) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL965113 0.78 TSHR (0.51) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL960876 0.78 HTT (0.52) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL4762874 0.76 HTT (0.50) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL24282131 0.75 MAPT (0.68) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL4138642 0.74 HTT (0.68) KDM4EMAPTTSHRHTTALOX15
SCHEMBL3712068 0.74 RAB9A (0.67) KDM4EMAPTTSHRHSD17B10HTT
SCHEMBL17629354 0.72 TSHR (0.53) KDM4EMAPTTSHRHTTALOX15
SCHEMBL27930399 0.72 HTT (0.59) KDM4EMAPTTSHRHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD KDM4E 2731/4885MAPT 2191/4885TSHR 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.