SCHEMBL112763

SCHEMBL112763

O=C1CCCCCCCCC1S

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA4 P22748 3/20 0.48
TRIM24 O15164 2/20 0.36
TRIM33 Q9UPN9 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MCL1 Q07820 1/20 0.35
CA6 P23280 2/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
TLR4 O00206 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11657362 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
Cyclohexane SCHEMBL8879285 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
Cyclopentane SCHEMBL8879018 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL822982 1.00
SCHEMBL4989703 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL28983235 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
Methane SCHEMBL27674323 0.97 KMT2A (0.50) KMT2ACA1CA2CA4TRIM24
SCHEMBL822956 0.97
Methane SCHEMBL8878704 0.95
Biphenyl SCHEMBL3157315 0.93 KMT2A (0.46) KMT2ACA1CA2CA4TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4442241-A2 RETINOL REPLACEMENT IN SKIN TREATMENT Symrise AG (DE) 2024-10-09 EP claimed
EP-3773445-B1 RETINOL REPLACEMENT IN SKIN TREATMENT SYMRISE AG (DE) 2024-07-24 EP claimed
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS CHICAGO ATLANTIC ADMIN, LLC 2022-10-20 US claimed
CN-107847772-B Pharmaceutical composition containing polyalkylene glycol derivative 西姆莱斯股份公司 2022-01-04 CN claimed
US-20210212983-A1 ORAL CANNABINOID DELIVERY FORMULATIONS WITH MOUTHFEEL EXPERIENCE ENHANCERS CHICAGO ATLANTIC ADMIN, LLC 2021-07-15 US claimed
US-20210045983-A1 RETINOL REPLACEMENT IN SKIN TREATMENT SYMRISE AG (DE) 2021-02-18 US claimed
EP-3773445-A1 RETINOL REPLACEMENT IN SKIN TREATMENT Symrise AG (DE) 2021-02-17 EP claimed
CN-111918637-A Retinol substitute in skin treatment 西姆莱斯有限公司 2020-11-10 CN claimed
WO-2019185923-A1 RETINOL REPLACEMENT IN SKIN TREATMENT SYMRISE AG (DE) 2019-10-03 WO claimed
US-20180185301-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES SYMRISE AG (DE) 2018-07-05 US claimed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO claimed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US claimed
WO-2006127738-A9 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2007-05-31 WO claimed
US-20060280852-A1 Vanilla-flavored compositions and delivery systems therefor CADBURY ADAMS USA LLC. 2006-12-14 US claimed
WO-2006130132-A1 VANILLA-FLAVORED COMPOSITIONS AND DELIVERY SYSTEMS THEREFOR CADBURY ADAMS USA LLC (US) 2006-12-07 WO claimed
WO-2006127738-A2 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127602-A2 CONFECTIONERY COMPOSITION INCLUDING AN ELASTOMERIC COMPONENT AND A COOKED SACCHARIDE COMPONENT CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127740-A2 INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127599-A2 CONFECTIONERY COMPOSITION INCLUDING AN ELASTOMERIC COMPONENT, A COOKED SACCHARIDE COMPONENT, AND A SENSATE CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
US-20020012640-A1 Cosmetic composition for stressed skin under extreme conditions JEFFERIES FINANCE LLC, AS COLLATERAL AGENT 2002-01-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS MB, MLEC, NISCH KMT2A 4605/4885CA1 3845/4885CA2 2859/4885
US-20210045983-A1 RETINOL REPLACEMENT IN SKIN TREATMENT RBP1, RBP4, LRAT KMT2A 3792/4885CA1 4821/4885CA2 4570/4885
US-20180185301-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES PARG, PARN, TRPV1 KMT2A 3114/4885CA1 2030/4885CA2 557/4885
US-20210212983-A1 ORAL CANNABINOID DELIVERY FORMULATIONS WITH MOUTHFEEL EXPERIENCE ENHANCERS CNR2, CNR1, CPNE4 KMT2A 2218/4885CA1 2883/4885CA2 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.