Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494220 | 0.95 | MAPT (0.72) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11490245 | 0.92 | HTT (0.58) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11297804 | 0.87 | LMNA (0.53) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11494906 | 0.87 | MAPT (0.53) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11263267 | 0.85 | LMNA (0.51) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11489859 | 0.84 | LMNA (0.50) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11482008 | 0.84 | HTT (0.50) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11488772 | 0.83 | HTT (0.49) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11302866 | 0.81 | HRH4 (0.47) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11275070 | 0.79 | HTT (0.71) | MAPTLMNAHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |