Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490245 | 0.88 | HTT (0.58) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11494906 | 0.83 | MAPT (0.53) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11276321 | 0.83 | MAPT (0.72) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11489859 | 0.81 | LMNA (0.50) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11482008 | 0.80 | HTT (0.50) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11494220 | 0.78 | MAPT (0.72) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11302866 | 0.76 | HRH4 (0.47) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL31225036 | 0.72 | CYP1A2 (0.58) | HTTALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL11499576 | 0.72 | HTT (0.43) | HTTALDH1A1MAPTLMNAHPGD | |
| SCHEMBL11277793 | 0.72 | HRH4 (0.44) | HTTALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |