Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286266 | 0.96 | PMP22 (0.45) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11285938 | 0.87 | PMP22 (0.47) | LMNASMN1; SMN2KMT2AADRB2CYP2D6 | |
| Nisbuterol SCHEMBL29385412 | 0.86 | KMT2A (0.49) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11286362 | 0.85 | KMT2A (0.53) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11286262 | 0.85 | SLC2A1 (0.40) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11286259 | 0.85 | SLC2A1 (0.40) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11286356 | 0.84 | ADRB2 (0.53) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11286975 | 0.83 | SLC2A1 (0.49) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| Alcohol SCHEMBL11286257 | 0.83 | SLC2A1 (0.38) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11288443 | 0.83 | KMT2A (0.46) | SLC2A1LMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |