Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11286257 | 0.97 | SLC2A1 (0.38) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11286266 | 0.88 | PMP22 (0.45) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11286085 | 0.87 | KMT2A (0.44) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11279308 | 0.87 | KMT2A (0.44) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11276374 | 0.85 | SLC2A1 (0.44) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| Alcohol SCHEMBL11290095 | 0.85 | KMT2A (0.42) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11286262 | 0.84 | SLC2A1 (0.40) | SLC2A1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11285934 | 0.83 | TBXA2R (0.35) | ALDH1A1MAPTADRB3ADRB2ADRB1 | |
| Alcohol SCHEMBL11290214 | 0.80 | GAA (0.36) | ALDH1A1HTTKMT2ATP53GAA | |
| SCHEMBL11279949 | 0.80 | HIF1A (0.42) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |