Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.69 |
| ▸ | MAOA | P21397 | 18/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015880 | 0.91 | MAOB (0.69) | MAOBMAOADRD2 | |
| SCHEMBL11285429 | 0.89 | MAOA (0.67) | MAOBMAOADRD2 | |
| SCHEMBL11276209 | 0.89 | MAOA (0.67) | MAOBMAOADRD2 | |
| SCHEMBL11276093 | 0.87 | MAOB (0.70) | MAOBMAOADRD2 | |
| SCHEMBL2842062 | 0.86 | MAOB (0.80) | MAOBMAOADRD2 | |
| SCHEMBL11266584 | 0.84 | MAOB (0.64) | MAOBMAOADRD2 | |
| SCHEMBL11278331 | 0.83 | MAOB (0.70) | MAOBMAOADRD2 | |
| SCHEMBL11272833 | 0.82 | MAOB (0.55) | MAOBMAOADRD2 | |
| SCHEMBL238817 | 0.81 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL29545160 | 0.81 | MAOB (0.72) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | disclosed |
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |