Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284863 | 0.77 | KIF11 (0.41) | RAB9ASMN1; SMN2ALDH1A1MAPTDAO | |
| SCHEMBL11276522 | 0.76 | RAB9A (0.44) | RAB9ACTNNB1WNT3ANPC1SMN1; SMN2 | |
| SCHEMBL811207 | 0.75 | KCNN4 (0.50) | KCNN4CYP2C9KCNE1KCNQ1 | |
| SCHEMBL13154113 | 0.71 | KCNN4 (0.42) | RAB9ANPC1ALDH1A1PKMKCNN4 | |
| SCHEMBL4697916 | 0.68 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2TP53KCNN4 | |
| SCHEMBL4696006 | 0.68 | MAOB (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11266900 | 0.67 | CNR1 (0.45) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28473076 | 0.67 | RAB9A (0.36) | RAB9ANPC1SMN1; SMN2HPGDKCNN4 | |
| SCHEMBL15145670 | 0.64 | KCNN4 (0.42) | NFKB1KCNN4CES2CES1KCNE1 | |
| SCHEMBL3366582 | 0.64 | KCNN4 (0.42) | RAB9ANPC1NFKB1KCNN4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344954-A | DIURETICS | AMERICAN CYANAMID COMPANY (US) | 1982-08-17 | — | — | US | disclosed |