Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 1.00 |
| ▸ | AR | P10275 | 5/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paramethasone SCHEMBL5188901 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11854095 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11856144 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11862589 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL6850206 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11126091 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11127301 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL19327163 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL11421133 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 | |
| Paramethasone SCHEMBL6850202 | 1.00 | PGR (1.00) | PGRARABCB11NR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346037-A | Base catalyzed acylation with enol esters | THE UPJOHN COMPANY (US) | 1982-08-24 | — | — | US | claimed |
| US-4346037-A | Base catalyzed acylation with enol esters | THE UPJOHN COMPANY (US) | 1982-08-24 | — | — | US | disclosed |