1,4-Butanediol

1,4-Butanediol

SCHEMBL11276754

O=C(O)c1ccc(C(=O)O)c(CCO)c1CCO.OCCCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
ACMSD Q8TDX5 1/20 0.37
PTPN1 P18031 2/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28346746 0.96 CYP1A2 (0.39) CYP1A2HTTALDH1A1ALOX15ACMSD
SCHEMBL29664884 0.93 CYP1A2 (0.48) CYP1A2ALDH1A1ALOX15ACMSDPTPN1
SCHEMBL125463 0.93 CYP1A2 (0.48) CYP1A2ALDH1A1ALOX15ACMSDPTPN1
SCHEMBL1193168 0.91 CYP1A2 (0.42) CYP1A2HTTALDH1A1ALOX15SELL
Ethylene Glycol SCHEMBL25436654 0.91 CYP1A2 (0.46) CYP1A2ALDH1A1ALOX15ACMSDPTPN1
SCHEMBL7742108 0.89 PPARA (0.41) CYP1A2HTTALDH1A1ALOX15PPARA
SCHEMBL1060065 0.89 CYP1A2 (0.44) CYP1A2HTTALDH1A1ALOX15SELL
SCHEMBL11276749 0.85 TDP1 (0.42) ALDH1A1KDM4ETDP1TSHR
SCHEMBL27364912 0.83 GABRP (0.41) CYP1A2ALDH1A1ALOX15ACMSDPTPN1
SCHEMBL7705466 0.83 CYP1A2 (0.39) CYP1A2ALDH1A1ALOX15ACMSDPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358508-A AUTOMOBILE OVERCOATINGS MITSUBISHI RAYON CO., LTD. (JP) 1982-11-09 US disclosed