SCHEMBL29664884

SCHEMBL29664884

O=C(O)c1ccc(C(=O)O)c(CCO)c1CCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
ALDH1A1 P00352 5/20 0.42
ALOX15 P16050 1/20 0.42
ACMSD Q8TDX5 1/20 0.40
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
PTPN1 P18031 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 3/20 0.38
TSHR P16473 2/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
FOLH1 Q04609 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CASP1 P29466 1/20 0.37
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125463 1.00 CYP1A2 (0.48) CYP1A2ALDH1A1ALOX15ACMSDSELL
Ethylene Glycol SCHEMBL25436654 0.98 CYP1A2 (0.46) CYP1A2ALDH1A1ALOX15ACMSDSELL
1,4-Butanediol SCHEMBL11276754 0.93 CYP1A2 (0.42) CYP1A2ALDH1A1ALOX15ACMSDSELL
SCHEMBL27364912 0.89 GABRP (0.41) CYP1A2ALDH1A1ALOX15ACMSDPTPN1
SCHEMBL28346746 0.89 CYP1A2 (0.39) CYP1A2ALDH1A1ALOX15ACMSDSELL
SCHEMBL7705466 0.89 CYP1A2 (0.39) CYP1A2ALDH1A1ALOX15ACMSDSELL
SCHEMBL7197448 0.86 GABRP (0.42) CYP1A2ALDH1A1ACMSDPTPN1TDP1
SCHEMBL1060065 0.86 CYP1A2 (0.44) CYP1A2ALDH1A1ALOX15SELLSELP
SCHEMBL9156347 0.86 ALDH1A1 (0.50) ALDH1A1ALOX15ACMSDPTPN1TDP1
SCHEMBL7524973 0.85 CYP1A2 (0.39) CYP1A2ALDH1A1ALOX15ACMSDPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115843291-A Process for producing high-purity bis- (2-hydroxyethyl) terephthalate, recycled polyethylene terephthalate, decolorization solvent, and process for purifying bis- (2-hydroxyethyl) terephthalate 辛特克株式会社 2023-03-24 CN claimed
WO-2025264744-A1 BUTYL METHYL TEREPHTHALATE COMPOSITIONS USEFUL AS PLASTICIZERS EASTMAN CHEMICAL COMPANY (US) 2025-12-26 WO disclosed
EP-4655342-A1 PROCESS FOR DEPOLYMERIZATION OF POLYALKYLENE TEREPHTHALATES IN AN EXTRUDER Evonik Operations GmbH (DE) 2025-12-03 EP disclosed
CN-120051566-A Enzyme variants and uses thereof 杉萨拉生态私人有限公司 2025-05-27 CN disclosed
CN-119570762-A BHET hydrolase designed based on reverse folding algorithm and preparation method thereof 上海交通大学 2025-03-07 CN disclosed
EP-4259706-B1 PLASTIC-DEGRADING SOLUTION INNOVAZIONE E SVILUPPO SOSTENIBILE S R L (IT) 2025-01-29 EP disclosed
EP-4497823-A1 A METHOD FOR SCREENING THE POLYMER-DEGRADING ENZYMES Vilnius University (LT) 2025-01-29 EP disclosed
WO-2024156568-A1 PROCESS FOR DEPOLYMERIZATION OF POLYALKYLENE TEREPHTHALATES IN AN EXTRUDER EVONIK OPERATIONS GMBH (DE) 2024-08-02 WO disclosed
EP-4259706-A1 PLASTIC-DEGRADING SOLUTION Innovazione e Sviluppo Sostenibile S.r.l. (IT) 2023-10-18 EP disclosed
CN-116685631-A Solutions for degrading plastics 创新与可持续发展有限责任公司 2023-09-01 CN disclosed
CN-115843291-A Process for producing high-purity bis- (2-hydroxyethyl) terephthalate, recycled polyethylene terephthalate, decolorization solvent, and process for purifying bis- (2-hydroxyethyl) terephthalate 辛特克株式会社 2023-03-24 CN disclosed
WO-2022123421-A1 PLASTIC-DEGRADING SOLUTION Innovazione E Sviluppo Sostenibile S.r.l. (IT) 2022-06-16 WO disclosed