Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276905 | 0.88 | MRGPRX4 (0.40) | MMP2MMP9BCHEALDH1A1 | |
| SCHEMBL11210926 | 0.85 | BCHE (0.52) | BCHE | |
| SCHEMBL11277117 | 0.82 | FFAR1 (0.46) | MAOBFFAR1PPARGMMEACE | |
| SCHEMBL15442613 | 0.79 | MAOB (0.62) | MAOBFFAR1PPARGADAMTS4MMP13 | |
| SCHEMBL19841942 | 0.75 | MAOB (0.64) | MAOBFFAR1PPARGMMEACE | |
| SCHEMBL11208145 | 0.74 | FFAR1 (0.46) | MAOBFFAR1HRH3BCHEALDH1A1 | |
| SCHEMBL18164548 | 0.73 | MAOB (0.70) | MAOBFFAR1PPARG | |
| SCHEMBL11283415 | 0.72 | HDAC3 (0.43) | FFAR1PPARGMMP2MMP9ALDH1A1 | |
| SCHEMBL14108486 | 0.72 | MAOB (0.64) | MAOBFFAR1PPARGMMP2MMP9 | |
| SCHEMBL11209448 | 0.72 | BCHE (0.48) | MAOBBCHEALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |