Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273897 | 0.89 | HDAC3 (0.39) | PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL11283415 | 0.84 | HDAC3 (0.43) | FFAR1PPARG | |
| SCHEMBL11208063 | 0.83 | FFAR1 (0.43) | FFAR1MAOB | |
| SCHEMBL11276815 | 0.82 | MAOB (0.49) | FFAR1PPARGMAOBSLC6A5MME | |
| SCHEMBL11211662 | 0.82 | SIGMAR1 (0.48) | — | |
| SCHEMBL11211010 | 0.77 | HDAC3 (0.48) | — | |
| SCHEMBL15442613 | 0.73 | MAOB (0.62) | FFAR1PPARGMAOBSLC6A5 | |
| SCHEMBL11208145 | 0.73 | FFAR1 (0.46) | FFAR1MAOB | |
| SCHEMBL18164548 | 0.72 | MAOB (0.70) | FFAR1PPARGMAOB | |
| SCHEMBL11209448 | 0.71 | BCHE (0.48) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |