Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276815 | 0.88 | MAOB (0.49) | MMP2MMP9BCHEALDH1A1 | |
| SCHEMBL11210926 | 0.85 | BCHE (0.52) | BCHEMEN1POLBMAPK1KMT2A | |
| SCHEMBL11283415 | 0.84 | HDAC3 (0.43) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL11273897 | 0.82 | HDAC3 (0.39) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL11279957 | 0.78 | RAB9A (0.44) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL4662934 | 0.75 | MAOB (0.45) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL14163891 | 0.74 | RXRA (0.56) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL11208145 | 0.74 | FFAR1 (0.46) | BCHEALDH1A1MEN1POLBMAPK1 | |
| SCHEMBL11209448 | 0.72 | BCHE (0.48) | BCHEALDH1A1MEN1POLBMAPK1 | |
| SCHEMBL11277117 | 0.70 | FFAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |