Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676663 | 0.90 | KCNN4 (0.50) | NPC1MAPTKCNN4ELANECYP2C19 | |
| SCHEMBL9416372 | 0.85 | PPARA (0.49) | NPC1LMNAMAPTCASP3SENP8 | |
| SCHEMBL11276779 | 0.79 | GAA (0.41) | NPC1MAPTELANECYP1A2GAA | |
| SCHEMBL11274148 | 0.79 | PPARA (0.56) | LMNAMAPTELANECYP2C9CYP2C19 | |
| SCHEMBL9416379 | 0.75 | PPARA (0.65) | LMNAMAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL10582932 | 0.74 | PPARA (0.51) | NPC1LMNAMAPTCASP3SENP8 | |
| SCHEMBL8667967 | 0.74 | CYP2C9 (0.48) | NPC1LMNAMAPTCASP3SENP8 | |
| SCHEMBL7288524 | 0.73 | KCNN4 (0.52) | LMNAMAPTKCNN4ELANECYP2C9 | |
| SCHEMBL7861289 | 0.72 | NPC1 (0.43) | NPC1LMNAMAPTCASP3SENP8 | |
| SCHEMBL8468475 | 0.72 | KCNN4 (0.50) | NPC1MAPTKCNN4ELANECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044972-A1 | Process for the preparation of compounds of 2-aryloxy-acrylic acid | BASF Aktiengesellschaft (DE) | 1982-02-03 | — | — | EP | disclosed |