Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | FABP2 | P12104 | 2/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121452 | 0.84 | PPARA (0.68) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11276779 | 0.82 | GAA (0.41) | PPARACYP1A2MAPTMEN1KMT2A | |
| SCHEMBL1676663 | 0.81 | KCNN4 (0.50) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11800181 | 0.80 | PPARA (0.58) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11276841 | 0.79 | NPC1 (0.48) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL21991231 | 0.79 | PPARA (0.62) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11684008 | 0.79 | PPARA (0.62) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL19183361 | 0.78 | OPRK1 (0.66) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11655524 | 0.78 | PPARA (0.51) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11354150 | 0.77 | PPARA (0.55) | PPARACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044972-A1 | Process for the preparation of compounds of 2-aryloxy-acrylic acid | BASF Aktiengesellschaft (DE) | 1982-02-03 | — | — | EP | disclosed |