SCHEMBL8468475

SCHEMBL8468475

COC(=O)C(C)(O)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.50
SRC P12931 1/20 0.50
ELANE P08246 2/20 0.45
ALDH1A1 P00352 1/20 0.41
MAPT P10636 3/20 0.41
TSHR P16473 1/20 0.41
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PPARG P37231 1/20 0.39
RAB9A P51151 3/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28644949 1.00 KCNN4 (0.50) KCNN4SRCELANEALDH1A1MAPT
SCHEMBL7288524 0.82 KCNN4 (0.52) KCNN4SRCELANEALDH1A1MAPT
SCHEMBL3409848 0.82 PPARA (0.46) ELANEALDH1A1MAPTTSHRPDK1
SCHEMBL8468153 0.82 PPARA (0.46) ELANEALDH1A1MAPTTSHRPDK1
SCHEMBL1676663 0.81 KCNN4 (0.50) KCNN4SRCELANEALDH1A1MAPT
SCHEMBL10654872 0.80 PPARA (0.55) ALDH1A1MAPTTSHRHPGDNPSR1
SCHEMBL8024659 0.80 PPARG (0.41) SRCELANEALDH1A1MAPTTSHR
SCHEMBL10654216 0.79 KCNN4 (0.48) KCNN4SRCELANEALDH1A1MAPT
SCHEMBL27580615 0.79 PDK1 (0.42) KCNN4SRCMAPTPDK1PDK2
SCHEMBL8468146 0.79 PPARG (0.38) KCNN4SRCELANEALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886209-A CATALYTIC ESTERIFICATION OF THE CHIRALIC CARBOXYLIC ACID IN PRESENCE OF A DISTILLABLE ACID CATALYST WITH AN ALCOHOL, WITHOUT PURIFICATION OF THE BOTTOMS PRODUCT, REPEATING THE ESTERIFICATION STEP BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed