Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127716 | 0.81 | GSK3B (0.64) | GSK3BPRKCBPRKCAPRKCGPRKCZ | |
| SCHEMBL6242476 | 0.77 | GSK3B (0.44) | GSK3BPRKCBPRKCAPRKCGPRKCZ | |
| SCHEMBL27502357 | 0.73 | DYRK1A (0.49) | GSK3BPRKCBPRKCAPRKCGPRKCZ | |
| SCHEMBL11096354 | 0.72 | CYP2E1 (0.51) | GSK3BPRKCBPRKCAHTR3ADYRK1A | |
| SCHEMBL2955240 | 0.71 | GSK3B (0.57) | GSK3BPRKCBPRKCAPRKCGPRKCZ | |
| SCHEMBL13890161 | 0.70 | KDM4E (0.58) | GSK3BPRKCAPOLBKMT2A | |
| SCHEMBL27490560 | 0.68 | RAB9A (0.51) | GAAFYN | |
| SCHEMBL13013275 | 0.67 | NR4A2 (0.56) | HTR3A | |
| SCHEMBL13670446 | 0.67 | GSK3B (0.65) | GSK3BPRKCBPRKCAPRKCGPRKCZ | |
| SCHEMBL15444636 | 0.66 | HTR3A (0.55) | GSK3BPRKCBPRKCAHTR3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845460-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140080210-A1 | Treatment of Pluripotent Cells | JANSSEN BIOTECH, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| EP-2283114-A2 | TREATMENT OF PLURIPOTENT CELLS | Centocor Ortho Biotech Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009132068-A2 | TREATMENT OF PLURIPOTENT CELLS | CENTOCOR ORTHO BIOTECH INC. (US) | 2009-10-29 | — | — | WO | disclosed |