Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 1/20 | 0.42 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.42 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289720 | 0.91 | ALOX15 (0.47) | — | |
| SCHEMBL11277106 | 0.82 | HTR2A (0.42) | POLMPOLKPOLLPOLHEPHX2 | |
| SCHEMBL11282410 | 0.82 | ALOX15 (0.55) | POLMPOLKPOLLPOLHTRPV1 | |
| SCHEMBL11281184 | 0.82 | ALOX15 (0.55) | POLMPOLKPOLLPOLHTRPV1 | |
| Hydrochloric Acid SCHEMBL11636402 | 0.80 | ALOX15 (0.55) | POLMPOLKPOLLPOLHTRPV1 | |
| SCHEMBL11281650 | 0.79 | ADRB3 (0.43) | POLMPOLKPOLLPOLHEPHX2 | |
| SCHEMBL11281645 | 0.78 | POLM (0.38) | POLMPOLKPOLLPOLHEPHX2 | |
| SCHEMBL11291258 | 0.77 | ALOX15 (0.44) | — | |
| SCHEMBL11288774 | 0.76 | ALOX15 (0.44) | — | |
| SCHEMBL11284329 | 0.74 | POLM (0.47) | POLMPOLKPOLLPOLHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |