Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
| ▸ | THRA | P10827 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277111 | 0.91 | POLM (0.42) | — | |
| SCHEMBL11282410 | 0.91 | ALOX15 (0.55) | ALOX15TOP2ASMPD1HSD17B3THRA | |
| SCHEMBL11281184 | 0.91 | ALOX15 (0.55) | ALOX15TOP2ASMPD1HSD17B3THRA | |
| Hydrochloric Acid SCHEMBL11636402 | 0.88 | ALOX15 (0.55) | ALOX15TOP2ASMPD1HSD17B3THRA | |
| SCHEMBL11291258 | 0.85 | ALOX15 (0.44) | ALOX15TOP2ASMPD1HSD17B3THRA | |
| SCHEMBL11288774 | 0.82 | ALOX15 (0.44) | ALOX15 | |
| SCHEMBL11286258 | 0.78 | ALOX15 (0.41) | ALOX15TOP2A | |
| SCHEMBL11283525 | 0.78 | MAPT (0.53) | ALOX15TOP2A | |
| SCHEMBL11289719 | 0.78 | ALOX15 (0.51) | ALOX15TOP2ASMPD1THRATHRB | |
| Hydrochloric Acid SCHEMBL11283520 | 0.77 | MAPT (0.54) | ALOX15TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |