SCHEMBL11277113

SCHEMBL11277113

CC1=C(C)C(C(=O)O)(C(=O)O)CCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
HAO1 Q9UJM8 1/20 0.35
FFAR3 O14843 1/20 0.32
RARB P10826 8/20 0.32
RXRA P19793 7/20 0.32
RARA P10276 7/20 0.32
RARG P13631 7/20 0.32
ALDH1A1 P00352 4/20 0.32
MAPT P10636 4/20 0.32
PTGS1 P23219 3/20 0.32
RXRB P28702 3/20 0.32
RXRG P48443 3/20 0.32
RORC P51449 2/20 0.32
CYP3A4 P08684 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
MAPK1 P28482 2/20 0.32
HTR2B P41595 2/20 0.32
BLM P54132 2/20 0.32
HIF1A Q16665 2/20 0.32
NR4A1 P22736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673147 0.79 CYP1A2 (0.39) CYP1A2HAO1FFAR3RARBRXRA
SCHEMBL10437018 0.77 CYP1A2 (0.43) CYP1A2HAO1FFAR3RARBRXRA
SCHEMBL486947 0.72 CYP1A2 (0.37) CYP1A2HAO1RARB
SCHEMBL7564849 0.71 HDAC4 (0.33) CYP1A2HAO1RARB
SCHEMBL2135859 0.70 CYP1A2 (0.36) CYP1A2HAO1ALDH1A1PTGS1DRD3
SCHEMBL9342959 0.68 CYP1A2 (0.51) CYP1A2HAO1RARBRXRARARA
SCHEMBL3264588 0.65 CYP2C19 (0.30) CYP2C19
Ethane SCHEMBL908993 0.65 AKR1C1 (0.32) FFAR3ALDH1A1LMNACYP2C19
SCHEMBL22122574 0.64 EED (0.40) CYP1A2HAO1MAPTCYP3A4HIF1A
SCHEMBL1817186 0.64 CCR2 (0.37) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049823-A1 Thermoplastic copolyester elastomer CELANESE ENGINEERING RESINS, INC. (US) 1982-04-21 EP claimed
CN-115703707-A Method for preparing cyclohexane diformate and cyclohexanedimethanol 中国科学院大连化学物理研究所 2023-02-17 CN disclosed