Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275630 | 0.90 | ACE (0.55) | ACECA2CTSSCTSKCTSB | |
| SCHEMBL7324443 | 0.90 | ACE (0.67) | ACECA2CTSSCTSKCTSB | |
| SCHEMBL1790255 | 0.87 | ACE (0.65) | ACECA2CTSSCTSKCTSB | |
| SCHEMBL7329244 | 0.82 | ACE (0.67) | ACECA2CTSSCTSKCTSB | |
| SCHEMBL10376903 | 0.82 | ACE (0.67) | ACECA2CTSSCTSKCTSB | |
| SCHEMBL7301113 | 0.81 | ACE (0.65) | ACECA2CTSSCTSKCTSB | |
| Putrescine SCHEMBL28493581 | 0.81 | ACE (0.69) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL795685 | 0.80 | ACE (0.79) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL606309 | 0.80 | ACE (0.79) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL21473784 | 0.80 | ACE (0.79) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316892-A | 2,6-C-Dimethyltyrosine1 -D-amino acid2 -ε-amino caproic and γ aminobutyric acid5 derivatives of methionine enkephalin | G. D. SEARLE & CO. (US) | 1982-02-23 | — | — | US | disclosed |