Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281772 | 0.83 | HTT (0.55) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL11281662 | 0.82 | NOTUM (0.42) | ALDH1A1MEN1KMT2ACHRM1PTGS1 | |
| SCHEMBL10679069 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL11275499 | 0.79 | KCNQ2 (0.52) | MEN1KMT2AGAAL3MBTL1NPSR1 | |
| SCHEMBL11282006 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL11219311 | 0.78 | PTGS1 (0.74) | ALDH1A1KDM4ECHRM1PTGS1MAPK1 | |
| SCHEMBL11279594 | 0.77 | MAPT (0.48) | ALDH1A1KDM4ELMNAMC4RGAA | |
| SCHEMBL11288764 | 0.77 | KCNQ2 (0.54) | KMT2ACHRM1PTGS1GAAL3MBTL1 | |
| SCHEMBL27741258 | 0.77 | POLB (0.54) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10674431 | 0.76 | MEN1 (0.41) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |