Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288764 | 0.98 | KCNQ2 (0.54) | KCNQ2NPC1HIF1AGAAMAPT | |
| SCHEMBL11766280 | 0.84 | ADRB1 (0.54) | MAPT | |
| SCHEMBL6081054 | 0.82 | KCNQ2 (0.56) | KCNQ2NPC1GAAMAPTNPSR1 | |
| SCHEMBL7900203 | 0.80 | GAA (0.49) | KCNQ2NPC1HIF1AGAAMAPT | |
| SCHEMBL12190503 | 0.79 | KEAP1 (0.52) | KCNQ2NPC1GAAMAPTL3MBTL1 | |
| SCHEMBL11277411 | 0.79 | ALDH1A1 (0.49) | GAANPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL11281772 | 0.79 | HTT (0.55) | KCNQ2NPC1GAAMAPTNPSR1 | |
| SCHEMBL5795776 | 0.78 | KEAP1 (0.55) | KCNQ2NPC1HIF1AGAAMAPT | |
| SCHEMBL5795484 | 0.78 | KEAP1 (0.55) | KCNQ2NPC1HIF1AGAAMAPT | |
| SCHEMBL4547918 | 0.77 | GAA (0.48) | KCNQ2NPC1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |