Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289623 | 0.92 | TBXA2R (0.41) | TBXA2RP2RX4CASP1PMP22ADRB2 | |
| SCHEMBL11282282 | 0.89 | PMP22 (0.39) | TBXA2RP2RX4CASP1PMP22ADRB2 | |
| SCHEMBL11277421 | 0.86 | PMP22 (0.51) | CASP1PMP22ADRB2ADRB1ADRB3 | |
| SCHEMBL11284492 | 0.84 | TBXA2R (0.37) | TBXA2RP2RX4CASP1PMP22ADRB2 | |
| SCHEMBL11283327 | 0.80 | TBXA2R (0.38) | TBXA2RCASP1PMP22ADRB3KDM4E | |
| SCHEMBL11280914 | 0.78 | HIF1A (0.45) | CASP1PMP22ADRB2ADRB1KDM4E | |
| SCHEMBL11283478 | 0.78 | ADRB2 (0.42) | CASP1PMP22ADRB2ADRB1ADRB3 | |
| SCHEMBL11286260 | 0.77 | PMP22 (0.40) | CASP1PMP22ADRB2ADRB1KDM4E | |
| SCHEMBL11289628 | 0.77 | PMP22 (0.47) | TBXA2RCASP1PMP22ADRB2ADRB1 | |
| SCHEMBL11558981 | 0.77 | SLC6A4 (0.38) | TBXA2RPMP22ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |