Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277415 | 0.92 | TBXA2R (0.39) | TBXA2RCASP1P2RX4ADRB2ADRB1 | |
| SCHEMBL11283327 | 0.88 | TBXA2R (0.38) | TBXA2RCASP1ADRB3L3MBTL1PMP22 | |
| SCHEMBL11284492 | 0.85 | TBXA2R (0.37) | TBXA2RCASP1P2RX4ADRB2ADRB1 | |
| SCHEMBL11289628 | 0.85 | PMP22 (0.47) | TBXA2RCASP1ADRB2ADRB1ADRB3 | |
| SCHEMBL11281271 | 0.83 | ACHE (0.40) | TBXA2RCASP1ADRB2ADRB1ADRB3 | |
| SCHEMBL11282160 | 0.81 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TDP1PMP22 | |
| SCHEMBL11287414 | 0.81 | TBXA2R (0.37) | TBXA2RCASP1ADRB2PMP22ACHE | |
| SCHEMBL11277077 | 0.81 | TBXA2R (0.37) | TBXA2RCASP1ADRB2PMP22ACHE | |
| Hydrochloric Acid SCHEMBL11282152 | 0.80 | TDP1 (0.46) | ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL11282282 | 0.80 | PMP22 (0.39) | TBXA2RCASP1P2RX4ADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |