Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986611 | 0.83 | PRCP (0.60) | PRCPHTR2AMAPTMEN1KMT2A | |
| SCHEMBL31121199 | 0.82 | PNMT (0.43) | PRCPALDH1A1MAPTDRD1DRD2 | |
| SCHEMBL4766983 | 0.79 | ALDH1A1 (0.40) | PRCPALDH1A1MAPTDRD1DRD2 | |
| SCHEMBL11308321 | 0.75 | ALDH1A1 (0.37) | PRCPALDH1A1MAPTPNMTMEN1 | |
| SCHEMBL30827217 | 0.75 | ALDH1A1 (0.37) | PRCPALDH1A1MAPTPNMTMEN1 | |
| SCHEMBL23873992 | 0.73 | PRCP (0.67) | PRCPHTR2AALDH1A1MAPTDRD1 | |
| SCHEMBL29990541 | 0.73 | PRCP (0.67) | PRCPHTR2AALDH1A1MAPTDRD1 | |
| SCHEMBL12321732 | 0.73 | PRCP (0.67) | PRCPHTR2AALDH1A1MAPTDRD1 | |
| SCHEMBL27456289 | 0.73 | SLC6A2 (0.40) | PRCPALDH1A1MAPTDRD1DRD2 | |
| Formaldehyde SCHEMBL28256666 | 0.73 | MAPK1 (0.36) | PRCPALDH1A1MAPTDRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |