Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12990842 | 0.95 | ESR2 (0.53) | ESR2NQO1HRH3RAB9AMAOA | |
| SCHEMBL9512520 | 0.93 | ESR2 (0.42) | ESR2NQO1HRH3MAOAMAOB | |
| SCHEMBL20118136 | 0.90 | ESR2 (0.49) | ESR2NQO1HRH3RAB9AMAOA | |
| SCHEMBL9586183 | 0.88 | NQO1 (0.61) | NQO1HRH3RAB9AMAOAMAOB | |
| SCHEMBL11277004 | 0.87 | RAB9A (0.56) | ESR2HRH3RAB9ANPC1 | |
| SCHEMBL11287806 | 0.87 | RAB9A (0.49) | ESR2HRH3RAB9AMAOAMAOB | |
| SCHEMBL9508530 | 0.87 | ESR2 (0.46) | ESR2NQO1HRH3RAB9AMAOA | |
| SCHEMBL5961794 | 0.87 | ESR2 (0.46) | ESR2NQO1HRH3RAB9AMAOA | |
| SCHEMBL10017500 | 0.85 | NQO1 (0.45) | NQO1RAB9ANPC1CASP3SENP8 | |
| SCHEMBL6453900 | 0.85 | RAB9A (0.42) | ESR2NQO1RAB9AGRM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7670502-B2 | Liquid crystal composition for bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20090143609-A1 | LIQUID CRYSTAL COMPOSITIONS AND THEIR USE IN LIQUID CRYSTAL DEVICES | IPS ALPHA SUPPORT CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143609-A1 | LIQUID CRYSTAL COMPOSITIONS AND THEIR USE IN LIQUID CRYSTAL DEVICES | GTF3C3, CCR3, OR10J3 | ESR2 3816/4885NQO1 4855/4885HRH3 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.