Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 3/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17947765 | 0.94 | SLC6A2 (0.50) | SLC6A2PTGS1TAAR1LTA4HADRB2 | |
| SCHEMBL23465595 | 0.94 | LTA4H (0.58) | SLC6A2PTGS1TAAR1LTA4HADRB2 | |
| SCHEMBL3173896 | 0.83 | SLC6A2 (0.58) | SLC6A2PTGS1LTA4HADRB2ADRB1 | |
| SCHEMBL10922516 | 0.81 | LMNA (0.67) | SLC6A2PTGS1LTA4HADRB2ADRB1 | |
| SCHEMBL19618912 | 0.81 | SCN4A (0.52) | SCN5ASCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL27038352 | 0.81 | LMNA (0.67) | SLC6A2PTGS1LTA4HADRB2ADRB1 | |
| SCHEMBL9479823 | 0.81 | SCN4A (0.52) | SCN5ASCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL8682212 | 0.81 | SLC6A4 (0.59) | SCN5ASCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL18295367 | 0.81 | SCN4A (0.52) | SCN5ASCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL27038560 | 0.81 | LMNA (0.67) | SLC6A2PTGS1LTA4HADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |