Diacetylisoproterenol

Diacetylisoproterenol

SCHEMBL11277673

CC(=O)Oc1ccc(C(O)CNC(C)C)cc1OC(C)=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A3 O75751 1/20 0.58
HIF1A Q16665 4/20 0.54
LMNA P02545 3/20 0.54
CYP3A4 P08684 3/20 0.54
ALDH1A1 P00352 2/20 0.54
ADRB2 P07550 5/20 0.54
MAPT P10636 5/20 0.54
KDM4E B2RXH2 4/20 0.54
TDP1 Q9NUW8 4/20 0.54
TSHR P16473 4/20 0.54
ADRB1 P08588 3/20 0.54
MAPK1 P28482 3/20 0.54
HSD17B10 Q99714 3/20 0.54
MEN1 O00255 3/20 0.54
CYP1A2 P05177 3/20 0.54
KMT2A Q03164 3/20 0.54
ADRB3 P13945 2/20 0.54
MTOR P42345 2/20 0.54
NFKB1 P19838 2/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diacetylisoproterenol SCHEMBL11287902 0.96 SLC22A3 (0.54) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11208066 0.88 ADRB2 (0.52) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11284384 0.87 SLC22A3 (0.57) SLC22A3HIF1ALMNACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL10899141 0.87 ADRB2 (0.51) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL23318966 0.85 HIF1A (0.72) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11526980 0.85 HIF1A (0.76) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11524503 0.84 SLC22A3 (0.53) SLC22A3HIF1ALMNACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL3207428 0.84 ADRB2 (0.77) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11527878 0.83 ADRB2 (0.52) SLC22A3HIF1ALMNACYP3A4ALDH1A1
SCHEMBL11287075 0.82 SLC22A3 (0.49) SLC22A3HIF1ALMNACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336400-A BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS STERLING DRUG INC. (US) 1982-06-22 US disclosed
US-4138581-A BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS STERLING DRUGS INC. (US) 1979-02-06 US disclosed