SCHEMBL1127777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL34473038	0.80	GAA (0.46)	MAPTLMNAKMT2AATMTDP1
	SCHEMBL21461564	0.80	GAA (0.46)	MAPTLMNAKMT2AATMTDP1
	SCHEMBL3690450	0.78	GAA (0.49)	MAPTLMNAKMT2AMEN1TDP1
	SCHEMBL29581400	0.75	NOTUM (0.48)	MAPTKMT2AMEN1ATMTDP1
	SCHEMBL307944	0.73	GAA (0.34)	MAPTLMNAKMT2AMEN1TDP1
	SCHEMBL23397300	0.72	HTR2C (0.37)	CYP19A1HTR2AHTR2CCSNK1D
	SCHEMBL1126913	0.72	HTR2A (0.39)	CYP19A1HTR2AHTR2CCSNK1D
	SCHEMBL29176018	0.72	TDP1 (0.37)	MAPTLMNAKMT2AMEN1ATM
	SCHEMBL16312602	0.71	MAPT (0.42)	MAPTLMNAKMT2AMEN1ATM
	SCHEMBL31431068	0.69	MAPT (0.38)	MAPTLMNAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.