Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276136 | 0.89 | LMNA (0.48) | HPGDMAPTTSHRMEN1KMT2A | |
| SCHEMBL11276133 | 0.89 | L3MBTL1 (0.46) | HPGDMAPTTSHRMEN1KMT2A | |
| SCHEMBL11277772 | 0.88 | MEN1 (0.55) | HPGDMAPTTSHRMEN1KMT2A | |
| SCHEMBL11270592 | 0.88 | LMNA (0.52) | HPGDMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11270588 | 0.88 | LMNA (0.52) | HPGDMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11268529 | 0.83 | ALDH1A1 (0.43) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1648216 | 0.82 | KMT2A (0.47) | HPGDMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11267592 | 0.81 | KMT2A (0.47) | HPGDMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11264175 | 0.80 | KLK7 (0.60) | MAPTMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11277245 | 0.80 | MGLL (0.48) | HPGDMAPTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |