Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041458 | 0.89 | PTGS1 (0.61) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL1393871 | 0.88 | PTGS1 (0.67) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL11571391 | 0.85 | PTGS2 (0.65) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL31375120 | 0.84 | PTGS2 (0.64) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL2944919 | 0.84 | PTGS2 (0.64) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL3281060 | 0.84 | PTGS2 (0.64) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL10041457 | 0.83 | PTGS2 (0.62) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL12896272 | 0.82 | PTGS2 (0.66) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL17464177 | 0.82 | PTGS2 (0.66) | PTGS1PGRADORA3SLC6A2PTGS2 | |
| SCHEMBL27932711 | 0.81 | PTGS2 (0.64) | PTGS1PGRADORA3SLC6A2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335251-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1982-06-15 | — | — | US | disclosed |
| US-4150137-A | ANTIINFLAMMATORY, ANTIPYRETIC, AND ANALGESIC AGENTS | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1979-04-17 | — | — | US | disclosed |