Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.61 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792870 | 0.91 | ALDH1A1 (0.58) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL6792877 | 0.91 | ALDH1A1 (0.58) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL19774810 | 0.90 | PTGS1 (0.57) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL10041458 | 0.89 | PTGS1 (0.61) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL11278076 | 0.88 | PTGS1 (0.60) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL4007604 | 0.87 | ALDH1A1 (0.58) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL8792364 | 0.87 | PTGS1 (0.52) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL1114395 | 0.86 | PTGS1 (0.53) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL15449778 | 0.86 | PTGS1 (0.53) | PTGS1PGRADORA3SLC6A2PPARG | |
| SCHEMBL5182481 | 0.86 | LMNA (0.56) | PTGS1PGRADORA3SLC6A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53053639-A | — | — | None | — | — | JP | disclosed |
| US-20250154181-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2025-05-15 | — | — | US | disclosed |
| US-12173021-B2 | Treprostinil prodrugs | UNITED THERAPEUTICS CORPORATION (US) | 2024-12-24 | — | — | US | disclosed |
| US-20240051979-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2024-02-15 | — | — | US | disclosed |
| US-11634443-B2 | Treprostinil prodrugs | UNITED THERAPEUTICS CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| EP-4017588-A1 | TREPROSTINIL PRODRUGS | United Therapeutics Corporation (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021041320-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2021-03-04 | — | — | WO | disclosed |
| US-20210054009-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2021-02-25 | — | — | US | disclosed |
| US-10570161-B2 | Unique dual-action therapeutics | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-02-25 | — | — | US | disclosed |
| US-20170143836-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | LEHIGH UNIVERSITY | 2017-05-25 | — | — | US | disclosed |
| US-20120010168-A1 | Unique Dual-Action Therapeutics | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-12 | — | — | US | disclosed |
| WO-2010051044-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | UNIVERSITY OF MEDICINE AND DENTISTRY (US) | 2010-05-06 | — | — | WO | disclosed |
| US-4223132-A | Selective conversion of benzyl alcohol carboxylates to the free acid form | SHIONOGI & CO., LTD. (JP) | 1980-09-16 | — | — | US | disclosed |
| US-4150137-A | ANTIINFLAMMATORY, ANTIPYRETIC, AND ANALGESIC AGENTS | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1979-04-17 | — | — | US | disclosed |
| JP-S5353639-A | NOVEL PHENYLPROPIONIC ACID ESTER DERIVATIVES | HISAMITSU PHARMACEUT CO INC | 1978-05-16 | — | — | JP | disclosed |
| JP-S05353639-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154181-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | PTGS1 127/4885PGR 143/4885ADORA3 751/4885 |
| US-20120010168-A1 | Unique Dual-Action Therapeutics | ACHE, PDE1A, PDE1C | PTGS1 28/4885PGR 1470/4885ADORA3 550/4885 |
| US-20170143836-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | ACHE, PDE1A, PDE1C | PTGS1 28/4885PGR 1470/4885ADORA3 550/4885 |
| US-20210054009-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | PTGS1 127/4885PGR 143/4885ADORA3 751/4885 |
| US-20240051979-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | PTGS1 127/4885PGR 143/4885ADORA3 751/4885 |
| US-12173021-B2 | Treprostinil prodrugs | TYMP, TK1, DCTPP1 | PTGS1 127/4885PGR 143/4885ADORA3 751/4885 |
| US-10570161-B2 | Unique dual-action therapeutics | ACHE, PDE1A, PDE1C | PTGS1 28/4885PGR 1569/4885ADORA3 440/4885 |
| US-11634443-B2 | Treprostinil prodrugs | TYMP, TK1, DCTPP1 | PTGS1 127/4885PGR 143/4885ADORA3 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.