Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265465 | 0.89 | CNR2 (0.42) | CNR2LMNAMAP3K14MEN1ALDH1A1 | |
| SCHEMBL11272103 | 0.85 | LMNA (0.40) | CNR2LMNAMAP3K14MEN1ALDH1A1 | |
| SCHEMBL10512812 | 0.83 | CNR2 (0.40) | CNR2NPC1RAB9ALMNAMAP3K14 | |
| SCHEMBL29102668 | 0.83 | LMNA (0.50) | CNR2NPC1RAB9ALMNAMAP3K14 | |
| SCHEMBL5776620 | 0.83 | MEN1 (0.42) | CNR2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL10536893 | 0.80 | CNR2 (0.38) | CNR2NPC1RAB9ALMNAMAP3K14 | |
| SCHEMBL11463498 | 0.79 | NPC1 (0.46) | CNR2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11197171 | 0.79 | NPC1 (0.40) | CNR2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL29225365 | 0.77 | TSHR (0.46) | NPC1RAB9AALDH1A1MAPTRECQL | |
| SCHEMBL11726600 | 0.77 | RECQL (0.51) | CNR2NPC1RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344943-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1982-08-17 | — | — | US | disclosed |