Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278151 | 0.85 | CNR2 (0.39) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL11265465 | 0.82 | CNR2 (0.42) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL4427821 | 0.82 | LMNA (0.53) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL3504148 | 0.82 | LMNA (0.41) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL29229 | 0.82 | LMNA (0.44) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL27925988 | 0.77 | ALDH1A1 (0.38) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL11199893 | 0.77 | ALDH1A1 (0.40) | LMNAMAP3K14MEN1ALDH1A1MAPT | |
| SCHEMBL11357348 | 0.77 | NR4A2 (0.47) | LMNAMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL13541632 | 0.76 | TSHR (0.48) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL11535104 | 0.76 | BRD4 (0.49) | LMNAALDH1A1MAPTKDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344943-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1982-08-17 | — | — | US | disclosed |