Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664843 | 0.85 | ADRA2C (1.00) | ADRA2CCYP19A1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL30256070 | 0.85 | ADRA2C (1.00) | ADRA2CCYP19A1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4817509 | 0.85 | ADRA2C (1.00) | ADRA2CCYP19A1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL29846165 | 0.85 | ADRA2C (1.00) | ADRA2CCYP19A1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4664253 | 0.85 | ADRA2C (1.00) | ADRA2CCYP19A1CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL11277181 | 0.81 | ADRA2C (0.70) | ADRA2CCYP19A1HMOX1IDO1 | |
| SCHEMBL29669977 | 0.81 | ADRA2C (0.70) | ADRA2CCYP19A1HMOX1IDO1 | |
| SCHEMBL20419588 | 0.81 | ADRA2C (0.72) | ADRA2CCYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11270380 | 0.80 | CYP19A1 (0.62) | ADRA2CCYP19A1HMOX1CYP51A1CYP8B1 | |
| SCHEMBL6391012 | 0.80 | ADRA2C (0.60) | ADRA2CCYP19A1CYP2C9HMOX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349556-A | Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |