Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278487 | 1.00 | DNM1 (0.33) | DNM1TSHRSMN1; SMN2OPRM1LCK | |
| SCHEMBL11286498 | 0.93 | OPRM1 (0.41) | DNM1OPRM1LCKPPARDZDHHC20 | |
| SCHEMBL11286499 | 0.93 | OPRM1 (0.41) | DNM1OPRM1LCKPPARDZDHHC20 | |
| SCHEMBL11280229 | 0.91 | LCK (0.41) | DNM1TSHROPRM1LCKPPARD | |
| SCHEMBL11288063 | 0.91 | LCK (0.41) | DNM1TSHROPRM1LCKPPARD | |
| SCHEMBL11280230 | 0.91 | LCK (0.41) | DNM1TSHROPRM1LCKPPARD | |
| SCHEMBL11288062 | 0.91 | LCK (0.41) | DNM1TSHROPRM1LCKPPARD | |
| SCHEMBL11277223 | 0.90 | DNM1 (0.39) | DNM1TSHRSMN1; SMN2OPRM1LCK | |
| SCHEMBL11277225 | 0.90 | DNM1 (0.39) | DNM1TSHRSMN1; SMN2OPRM1LCK | |
| SCHEMBL11281635 | 0.85 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000555-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |