Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589760 | 0.83 | PLAUR (0.47) | EGFRKDM4EGPR3PLAURALDH1A1 | |
| SCHEMBL30124132 | 0.75 | EGFR (0.54) | EGFRKDM4EGPR3PIK3CDPIK3CA | |
| SCHEMBL35632 | 0.75 | EGFR (0.54) | EGFRKDM4EGPR3PIK3CDPIK3CA | |
| SCHEMBL8967704 | 0.74 | CYP3A4 (0.46) | KDM4EGPR3PLAURMAPTALDH1A1 | |
| SCHEMBL30362637 | 0.74 | ACHE (0.57) | EGFRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL28614688 | 0.74 | ACHE (0.57) | EGFRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL10916482 | 0.72 | ESR1 (0.47) | EGFRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL23649973 | 0.69 | EGFR (0.52) | EGFRKDM4EGPR3PIK3CDPIK3CA | |
| SCHEMBL15796997 | 0.69 | KDM4E (0.65) | EGFRPDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL18099789 | 0.68 | KDM4E (0.50) | EGFRPDE5AKDM4EGPR3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311700-A | ANTIULCER, GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-01-19 | — | — | US | disclosed |
| EP-0024582-A1 | Benzodiazepinones, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| WO-1981000568-A1 | BENZODIAZEPINONES,A PROCESS FOR THEIR PREPARATION,THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-03-05 | — | — | WO | disclosed |