SCHEMBL11278684

SCHEMBL11278684

CC(C)=CCC1(C)CC2C(CC1=O)C2(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.36
ACHE P22303 2/20 0.33
PNLIP P16233 1/20 0.32
IKBKB O14920 1/20 0.30
XDH P47989 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18603988 1.00 PTPN1 (0.36) PTPN1ACHEPNLIPIKBKBXDH
SCHEMBL27084024 1.00 PTPN1 (0.36) PTPN1ACHEPNLIPIKBKBXDH
SCHEMBL8610503 0.66 PTPN1 (0.41) PTPN1
SCHEMBL4415300 0.65 XDH (0.33) ACHEXDH
SCHEMBL2184267 0.64 NFE2L2 (0.36) PNLIPIKBKB
SCHEMBL2183023 0.62 IKBKB (0.32) IKBKB
SCHEMBL4423005 0.61 IKBKB (0.36) PNLIPIKBKB
SCHEMBL11301927 0.60 IKBKB (0.33) PTPN1PNLIPIKBKB
SCHEMBL4412683 0.60
SCHEMBL2181902 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
US-20190010293-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20190010427-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
WO-2019010263-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
US-4322318-A Novel prenyl 4-caranones GIVAUDAN CORPORATION (US) 1982-03-30 US claimed
US-4278817-A ODORANTS GIVAUDAN CORPORATION (US) 1981-07-14 US claimed
EP-0011877-B1 CARANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS PERFUMES, AND PERFUME COMPOSITIONS CONTAINING THEM L. Givaudan & Cie Société Anonyme (CH) 1981-05-20 EP claimed
EP-0011877-A1 Carane derivatives, process for their preparation, their use as perfumes, and perfume compositions containing them L. Givaudan & Cie Société Anonyme (CH) 1980-06-11 EP claimed
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP disclosed
EP-3649184-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP disclosed
WO-2019010263-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO disclosed
US-20190010293-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US disclosed
US-20190010427-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US disclosed
WO-2019010265-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO disclosed
US-4322318-A Novel prenyl 4-caranones GIVAUDAN CORPORATION (US) 1982-03-30 US disclosed
US-4291021-A Novel macrolide antibiotics and preparation thereof TOYO JOZO COMPANY, LTD. (JP) 1981-09-22 US disclosed
US-4278817-A ODORANTS GIVAUDAN CORPORATION (US) 1981-07-14 US disclosed
EP-0011877-B1 CARANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS PERFUMES, AND PERFUME COMPOSITIONS CONTAINING THEM L. Givaudan & Cie Société Anonyme (CH) 1981-05-20 EP disclosed
EP-0011877-A1 Carane derivatives, process for their preparation, their use as perfumes, and perfume compositions containing them L. Givaudan & Cie Société Anonyme (CH) 1980-06-11 EP disclosed