SCHEMBL11278685

SCHEMBL11278685

CCc1ccc(C(=O)Cl)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TRPA1 O75762 1/20 0.41
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
NR1H4 Q96RI1 1/20 0.40
EGFR P00533 1/20 0.40
PLK1 P53350 1/20 0.40
AGTR1 P30556 1/20 0.40
PKM P14618 1/20 0.40
RARB P10826 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
BCL2 P10415 1/20 0.38
SRD5A2 P31213 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28509946 0.85 CA1 (0.42) ALDH1A1GAAMAPTNR1H4RARB
SCHEMBL31635558 0.83 CYP4F2 (0.47) ALDH1A1GAAMAPTNR1H4RARB
SCHEMBL2343149 0.82 ALDH1A1 (0.55) ALDH1A1TRPA1NR1H4PLK1AGTR1
SCHEMBL9214669 0.82 ALDH1A1 (0.45) ALDH1A1TRPA1GAAMAPTNR1H4
SCHEMBL11806978 0.82 ALDH1A1 (0.45) ALDH1A1TRPA1NR1H4EGFRPLK1
SCHEMBL8875590 0.81 MAPT (0.43) ALDH1A1TRPA1GAAMAPTNR1H4
SCHEMBL23960204 0.81 MKNK1 (0.44) ALDH1A1TRPA1MAPTPLK1PKM
SCHEMBL14387517 0.80 KMT2A (0.46) ALDH1A1GAAMAPTNR1H4SRD5A2
SCHEMBL5502090 0.79 ALDH1A1 (0.49) ALDH1A1GAAMAPTPLK1PKM
SCHEMBL777208 0.79 ALDH1A1 (0.42) ALDH1A1TRPA1GAAMAPTNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336400-A BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS STERLING DRUG INC. (US) 1982-06-22 US disclosed
US-RE30241-E BRONCHODILATION, ADRENERGIC STIMULANTS STERLING DRUG INC. (US) 1980-03-25 US disclosed
US-4138581-A BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS STERLING DRUGS INC. (US) 1979-02-06 US disclosed