SCHEMBL777208

SCHEMBL777208

CCc1ccc(C(=O)SC(=O)c2ccc(CC)cc2C)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TRPA1 O75762 1/20 0.39
PKM P14618 1/20 0.39
PLK1 P53350 1/20 0.39
RARB P10826 1/20 0.38
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 2/20 0.37
BCL2 P10415 1/20 0.37
SRD5A2 P31213 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
EGFR P00533 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
AGTR1 P30556 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
AKR1C3 P42330 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11806978 0.81 ALDH1A1 (0.45) ALDH1A1TRPA1PKMPLK1RARB
SCHEMBL2343149 0.81 ALDH1A1 (0.55) ALDH1A1TRPA1PLK1RARBRAB9A
SCHEMBL9214669 0.81 ALDH1A1 (0.45) ALDH1A1TRPA1PKMPLK1RARB
SCHEMBL23960204 0.79 MKNK1 (0.44) ALDH1A1TRPA1PKMPLK1RARB
SCHEMBL11278685 0.79 ALDH1A1 (0.44) ALDH1A1TRPA1PKMPLK1RARB
SCHEMBL5502090 0.78 ALDH1A1 (0.49) ALDH1A1PKMPLK1TSHRGAA
SCHEMBL4518402 0.76 PLK1 (0.59) ALDH1A1PLK1RAB9ASMN1; SMN2NR1H4
SCHEMBL4518802 0.76 ALDH1A1 (0.41) ALDH1A1TRPA1PKMPLK1RARB
SCHEMBL775141 0.76 KMT2A (0.49) ALDH1A1PKMRAB9ASMN1; SMN2MAPT
SCHEMBL10277322 0.75 ALDH1A1 (0.40) ALDH1A1TRPA1PKMPLK1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed