Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295863 | 0.85 | PTPN1 (0.63) | CA2PTGS1PTPN1PTGS2CA1 | |
| SCHEMBL11268431 | 0.81 | PTGS1 (0.46) | CA2PTGS1PTPN1PTGS2GAA | |
| SCHEMBL11283301 | 0.79 | PTGS1 (0.44) | CA2PTGS1PTPN1PTGS2CA1 | |
| SCHEMBL6000980 | 0.77 | PTPN1 (0.63) | CYSLTR2CYSLTR1CA2PTGS1PTPN1 | |
| SCHEMBL11279450 | 0.76 | PTGS1 (0.39) | CA2PTGS1PTPN1PTGS2PGR | |
| SCHEMBL6000987 | 0.74 | PTGS1 (0.55) | CYSLTR2CYSLTR1CA2PTGS1PTPN1 | |
| SCHEMBL7996154 | 0.73 | L3MBTL1 (0.52) | GAANTRK1 | |
| SCHEMBL14689917 | 0.73 | PTGS1 (0.63) | CYSLTR2CYSLTR1CA2PTGS1PTPN1 | |
| SCHEMBL18297880 | 0.72 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1CA2PTGS1PTPN1 | |
| SCHEMBL11299451 | 0.71 | PTGS1 (0.42) | CA2PTGS1PTGS2CA1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345077-A | Certain herbicidal N-(meta-(6-chloro-3-pyridazinyloxy)phenyl)trifluoromethanesulfonamides | SHELL OIL COMPANY (US) | 1982-08-17 | — | — | US | disclosed |
| US-4345077-A | Certain herbicidal N-(meta-(6-chloro-3-pyridazinyloxy)phenyl)trifluoromethanesulfonamides | SHELL OIL COMPANY (US) | 1982-08-17 | — | — | US | disclosed |
| US-4345077-A | Certain herbicidal N-(meta-(6-chloro-3-pyridazinyloxy)phenyl)trifluoromethanesulfonamides | SHELL OIL COMPANY (US) | 1982-08-17 | — | — | US | disclosed |