Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000356 | 0.86 | PTPN1 (0.81) | PTPN1CA2PGRNR3C1AR | |
| SCHEMBL6001500 | 0.85 | PTPN1 (0.86) | PTPN1CA2PTGS1PTGS2PGR | |
| SCHEMBL14689917 | 0.83 | PTGS1 (0.63) | PTPN1CA2CYSLTR2CYSLTR1PTGS1 | |
| SCHEMBL18297880 | 0.79 | CYSLTR2 (0.50) | PTPN1CA2CYSLTR2CYSLTR1PTGS1 | |
| SCHEMBL216185 | 0.79 | PTPN1 (0.62) | PTPN1CA2PTGS1PTGS2MEN1 | |
| SCHEMBL6526296 | 0.79 | CYSLTR2 (0.58) | PTPN1CA2CYSLTR2CYSLTR1PTGS1 | |
| SCHEMBL7262769 | 0.79 | ACLY (0.56) | CA2ACLYPGRMEN1KMT2A | |
| SCHEMBL28178583 | 0.79 | PGR (0.72) | ACLYPGRNR3C1MEN1KMT2A | |
| SCHEMBL6000987 | 0.78 | PTGS1 (0.55) | PTPN1CA2CYSLTR2CYSLTR1PTGS1 | |
| SCHEMBL6475739 | 0.78 | PTPN1 (0.48) | PTPN1CA2CYSLTR2CYSLTR1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | PTPN1 509/4885CA2 3839/4885CYSLTR2 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.