Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033877 | 0.84 | PDE3B (0.44) | MCL1ALBBCL2KDM4EATM | |
| SCHEMBL11324130 | 0.83 | CYP1A2 (0.44) | MCL1ALBBCL2KDM4EPDE3B | |
| SCHEMBL9213988 | 0.82 | GPR84 (0.41) | MCL1ALBBCL2KDM4EATM | |
| SCHEMBL11222527 | 0.77 | KDM4E (0.50) | KDM4EATMALDH1A1TSHR | |
| SCHEMBL11219891 | 0.77 | HTR1D (0.52) | KDM4EATMALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL11858150 | 0.76 | KDM4E (0.49) | KDM4EATMALDH1A1TSHR | |
| SCHEMBL11282430 | 0.76 | ALDH1A1 (0.47) | KDM4EPDE3BPDE3AALDH1A1TSHR | |
| SCHEMBL11308915 | 0.76 | KMT2A (0.53) | MCL1ALBBCL2KDM4EALDH1A1 | |
| SCHEMBL11322539 | 0.76 | PDE3B (0.63) | KDM4EPDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL11319689 | 0.76 | ADRB2 (0.42) | MCL1ALBBCL2KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |