Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908709 | 0.90 | CYP2C19 (0.54) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL7117673 | 0.80 | CYP2C19 (1.00) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL374864 | 0.78 | MDM2 (0.45) | ALOX15CYP2C9MDM2HTR2AHTR2C | |
| SCHEMBL3624706 | 0.77 | HTR1D (0.54) | CYP2C19ALOX15CYP2D6CYP1A2HTR1D | |
| SCHEMBL12309154 | 0.75 | HSPA5 (0.64) | CYP2C19MAPK1HTTCYP2D6CYP1A2 | |
| SCHEMBL199679 | 0.74 | CYP2C19 (0.53) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL28151708 | 0.73 | CYP2C19 (0.52) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL9194409 | 0.73 | CYP2C19 (0.66) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL196675 | 0.73 | CYP2C19 (0.61) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL199386 | 0.73 | CYP2C19 (0.61) | CYP2C19ALOX15MAPK1HTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322304-A | ANTIOXIDANTS | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | disclosed |