Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544911 | 0.78 | OPRM1 (0.34) | OPRM1JAK3ALDH1A1BLMDPP4 | |
| SCHEMBL967589 | 0.78 | ALDH1A1 (0.36) | OPRM1JAK3ALDH1A1BLMDPP4 | |
| SCHEMBL27262316 | 0.77 | OPRM1 (0.32) | OPRM1JAK3ALDH1A1 | |
| SCHEMBL27262314 | 0.77 | OPRM1 (0.32) | OPRM1JAK3ALDH1A1 | |
| SCHEMBL5970364 | 0.76 | OPRM1 (0.33) | OPRM1JAK3ALDH1A1BLMDPP4 | |
| Hydrochloric Acid SCHEMBL6026725 | 0.76 | ALDH1A1 (0.35) | OPRM1JAK3ALDH1A1BLMDPP4 | |
| SCHEMBL13713515 | 0.75 | ALDH1A1 (0.39) | OPRM1JAK3ALDH1A1DPP4 | |
| SCHEMBL10203871 | 0.72 | ALDH1A1 (0.37) | OPRM1JAK3ALDH1A1DPP4 | |
| SCHEMBL23343734 | 0.69 | JAK3 (0.39) | OPRM1JAK3ALDH1A1 | |
| SCHEMBL12224351 | 0.69 | ALDH1A1 (0.38) | OPRM1JAK3ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313948-A | Hypotensive imidazole substituted mercapto-1-oxopropyl-L-prolines | E. R. SQUIBB & SONS, INC. (US) | 1982-02-02 | — | — | US | disclosed |