Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26995521 | 0.84 | HPGD (0.60) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL320807 | 0.83 | HPGD (0.68) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL11111266 | 0.82 | GAA (0.62) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL868147 | 0.81 | EPHX2 (0.58) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL10585628 | 0.81 | TRPV1 (0.83) | HPGDGAAATMTRPV1CNR1 | |
| Hydrochloric Acid SCHEMBL11105183 | 0.81 | GAA (0.60) | HPGDGAAATMTRPV1CNR1 | |
| Bromide SCHEMBL11105861 | 0.81 | GAA (0.60) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL6289951 | 0.79 | HPGD (0.68) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL4153733 | 0.79 | HPGD (0.79) | HPGDGAAATMTRPV1CNR1 | |
| SCHEMBL5878927 | 0.79 | HPGD (0.68) | HPGDGAAATMTRPV1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033310-A1 | MODULATORS OF REV-ERB | KAMENECKA THEODORE MARK (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |